GHRP-2 (Growth Hormone Releasing Peptide-2, Pralmorelin, KP-102) is a synthetic hexapeptide derived from enkephalin, engineered as a potent, selective agonist of the ghrelin receptor (GHS-R1a, growth hormone secretagogue receptor) [citation:5][citation:6][citation:7]. Unlike GHRH analogs that act directly on the pituitary, GHRP-2 exerts its GH-releasing activity through dual hypothalamic and pituitary mechanisms, synergizing with endogenous GHRH while demonstrating superior resistance to enzymatic degradation [citation:1][citation:6]. As one of the most extensively characterized synthetic GH secretagogues, GHRP-2 serves as a precise research tool for investigating somatotropic axis regulation, metabolic adaptation, and pulsatile GH dynamics in controlled experimental systems [citation:6][citation:10].